Paid Clinical Trials in San Francisco, CA
As of July 2026, 1,365 paid clinical trials are recruiting in San Francisco, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
San Francisco offers studies at sites including University of California, San Francisco for conditions such as Breast Cancer, Prostate Cancer, Heart Failure, HIV. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in San Francisco
Trials by drug in San Francisco
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Newly added in San Francisco
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
SONATA LIFU for OCD
An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC
Social, Structural, and Lifestyle Drivers of Prostate Cancer Disparities
Neonatal White Matter Injury Trial (WRAP)
Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' Disease
1,100 clinical trials
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study of Brenipatide in Participants With Opioid Use Disorder
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
A Study of Brenipatide in Participants With Alcohol Use Disorder
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Top Research Study Locations in San Francisco
Researchers run research studies in San Francisco, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of California, San Francisco | Prostate Cancer, Glioblastoma, Epilepsy | 324 |
| University of California San Francisco | Multiple Myeloma, Prostate Cancer, Breast Cancer | 163 |
| Power Life Sciences | Acne, Anorexia, Anorexia Nervosa | 61 |
| UCSF Medical Center-Mission Bay | B Acute Lymphoblastic Leukemia, Neuroblastoma, Recurrent Malignant Solid Neoplasm | 37 |
| UCSF | Colorectal Cancer, Tricuspid Valve Disease, ADHD | 33 |
| Kaiser Permanente-San Francisco | Stage IV Lung Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma | 33 |
| Zuckerberg San Francisco General Hospital | Cardiovascular Diseases, HIV, Healthy | 25 |
| UCSF Helen Diller Family Comprehensive Cancer Center | Advanced Breast Cancer, Breast Cancer, Prostate Cancer | 23 |
| California Pacific Medical Center-Pacific Campus | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 22 |
| UCSF Medical Center | Stroke, Aneurysm, Aneurysm, Intracranial | 22 |
| University of California | Aortic Valve Regurgitation, Aortic Valve Stenosis, Articular Cartilage | 19 |
| San Francisco VA Medical Center, San Francisco, CA | PTSD, Sleep Initiation and Maintenance Disorders, Aging | 16 |
| UCSF Benioff Children's Hospital | 4H Syndrome, ADLD, AGS | 14 |
| University of California, San Francisco (UCSF) | Colorectal Cancer, Non-small Cell Lung Cancer, Acquired Resistance to KRAS G12C Inhibitor | 14 |
| California Pacific Medical Center | Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Melanoma | 13 |
| San Francisco General Hospital | HIV, HIV Infections, Intracerebral Hemorrhage | 12 |
| Alethios, Inc. | Beverage Intake, Caffeine, Healthy | 11 |
| San Francisco Research Institute | Women Health, Anxiety, Cognitive Decline | 10 |
| San Francisco VA Medical Center | Atopic Dermatitis, Eczema, Atopic Dermatitis (Eczema) | 10 |
| UCSF Medical Center-Parnassus | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 8 |
| University of California - San Francisco | Bladder Cancer, Diabetes, Diabetic Foot | 8 |
| University of California San Francisco (UCSF) | Melanoma, Advanced Solid Tumors, Angiosarcoma | 8 |
| University of California at San Francisco | Advanced Tumors, Aortic Valve Disease, Aortic Valve Stenosis | 8 |
| University of San Francisco | Cone Rod Dystrophy, Juvenile Macular Degeneration, Stargardt Disease | 7 |
| UCSF Medical Center at Mission Bay | Breast Cancer, Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal) | 6 |
Active & Upcoming Studies in San Francisco (2026)
Recruiting trials in San Francisco grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (409 active studies)
- Prenatal Transplantation for Fetuses With Fanconi Anemia · Phase 1, Phase 2 · Agnieszka Czechowicz
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial · Phase 3 · National Cancer Institute (NCI)
Neurology & pain (83 active studies)
- Alzheimer's Tau Platform: Regimen A - AADvac1 · Phase 2 · Paul S. Aisen
- An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service · Phase 3 · University of California, San Francisco
Cardiovascular (83 active studies)
- Naloxone for Opioid Associated Out of Hospital Cardiac Arrest · Phase 2 · University of California, San Francisco
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
Mental health & behavior (51 active studies)
- Mechanisms Evaluating Striatal Systems Imaging: LIFU Effects & Outcomes · University of California, San Francisco
- Pilot Study of an Adapted Partner Navigation Intervention Booster Session for Sustained Healthcare Engagement Among People Who Inject Drugs · University of California, San Francisco
HIV / STI (45 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- Pilot Study of an Adapted Partner Navigation Intervention Booster Session for Sustained Healthcare Engagement Among People Who Inject Drugs · University of California, San Francisco
Diabetes & metabolic (38 active studies)
- PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study · Phase 3 · University of Florida
- Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese · Phase 2 · Biomed Industries, Inc.
Pediatric (24 active studies)
- Prenatal Transplantation for Fetuses With Fanconi Anemia · Phase 1, Phase 2 · Agnieszka Czechowicz
- Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children · Duke University
Eye & vision (19 active studies)
- Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center · University of California, San Francisco
- Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes · University of California, San Francisco
Vaccines (13 active studies)
- Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC) · EARLY_Phase 1 · University of California, Davis
- A Study to Assess Anktiva in Patients With Long Covid-19. · Phase 2 · ImmunityBio, Inc.
Common conditions studied in San Francisco
- Breast Cancer (28 active studies)
- Prostate Cancer (28 active studies)
- Heart Failure (18 active studies)
- Cancer (15 active studies)
- HIV (14 active studies)
- Solid Tumor (13 active studies)
Leading research sponsors in San Francisco
- University of California, San Francisco
- Power Life Sciences Inc.
- National Cancer Institute (NCI)
- Children's Oncology Group
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in San Francisco?
There are approximately 1,365 recruiting clinical trials in San Francisco, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Francisco pay participants?
Most recruiting trials in San Francisco compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Francisco?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Francisco?
The most common conditions under active study in San Francisco include Breast Cancer (28), Prostate Cancer (28), Heart Failure (18), Cancer (15), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Francisco?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Francisco on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Francisco?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Francisco?
Recruiting research sites in San Francisco include University of California, San Francisco, University of California San Francisco, Power Life Sciences, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Francisco right now?
The largest active categories in San Francisco are Cancer & tumors (409), Neurology & pain (83), Cardiovascular (83). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.