Paid Clinical Trials in San Francisco, CA
As of September 2026, 1,328 paid clinical trials are recruiting in San Francisco, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
San Francisco offers studies at sites including University of California, San Francisco for conditions such as Breast Cancer, Prostate Cancer, Heart Failure, HIV. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in San Francisco
Trials by drug in San Francisco
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Newly added in San Francisco
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Validation of Biomarkers for Long COVID in the LIINC Viral Immunopathogenesis and Persistence Repeat Donor Cohort (VIPER)
A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy
A Prompt REstart Study of Renin-Angiotensin System Inhibitors After Acute Kidney Injury
A Study of Olezarsen for the Treatment of Familial Chylomicronemia Syndrome (FCS) in Pediatric Participants
SONATA LIFU for OCD
1,088 clinical trials
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
A Study of Brenipatide in Participants With Opioid Use Disorder
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
A Study of Brenipatide in Participants With Alcohol Use Disorder
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Top Research Study Locations in San Francisco
Researchers run research studies in San Francisco, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of California, San Francisco | Prostate Cancer, Glioblastoma, Parkinson Disease | 317 |
| University of California San Francisco | Prostate Cancer, Breast Cancer, Multiple Myeloma | 167 |
| Power Life Sciences | Acne, Anorexia, Anorexia Nervosa | 42 |
| UCSF Medical Center-Mission Bay | B Acute Lymphoblastic Leukemia, Neuroblastoma, Acute Myeloid Leukemia | 34 |
| Kaiser Permanente-San Francisco | Stage IV Lung Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma | 32 |
| UCSF | Colorectal Cancer, ADHD, ALK-Positive Lung Cancer | 30 |
| Zuckerberg San Francisco General Hospital | Cardiovascular Diseases, HIV, Healthy | 26 |
| California Pacific Medical Center-Pacific Campus | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 22 |
| UCSF Medical Center | Stroke, Aneurysm, Aneurysm, Intracranial | 22 |
| UCSF Helen Diller Family Comprehensive Cancer Center | Advanced Breast Cancer, Breast Cancer, Solid Tumor, Adult | 20 |
| University of California | Aortic Valve Regurgitation, Aortic Valve Stenosis, Astrocytoma, Grade IV | 17 |
| San Francisco VA Medical Center, San Francisco, CA | PTSD, Sleep Initiation and Maintenance Disorders, Aging | 16 |
| UCSF Benioff Children's Hospital | 4H Syndrome, ADLD, AGS | 14 |
| University of California, San Francisco (UCSF) | Colorectal Cancer, Non-small Cell Lung Cancer, Acquired Resistance to KRAS G12C Inhibitor | 14 |
| San Francisco General Hospital | HIV, HIV Infections, Intracerebral Hemorrhage | 12 |
| California Pacific Medical Center | Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Melanoma | 11 |
| San Francisco Research Institute | Women Health, Anxiety, Cognitive Decline | 10 |
| Alethios, Inc. | Abdominal Discomfort, Digestive Health, Digestive Well Being | 9 |
| San Francisco VA Medical Center | Atopic Dermatitis, Eczema, Atopic Dermatitis (Eczema) | 9 |
| University of California - San Francisco | Diabetes, Diabetic Foot, Diabetic Foot Ulcer | 8 |
| University of California San Francisco (UCSF) | Melanoma, Advanced Solid Tumors, Angiosarcoma | 8 |
| UCSF Medical Center at Mission Bay | Breast Cancer, Neoplasm Metastasis, Atrial Fibrillation (AF) | 7 |
| UCSF Medical Center-Parnassus | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 7 |
| University of California at San Francisco | Aortic Valve Disease, Aortic Valve Stenosis, Brain Tumor | 7 |
| University of San Francisco | Cone Rod Dystrophy, Juvenile Macular Degeneration, Stargardt Disease | 7 |
Active & Upcoming Studies in San Francisco (2026)
Recruiting trials in San Francisco grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (392 active studies)
- Prenatal Transplantation for Fetuses With Fanconi Anemia · Phase 1, Phase 2 · Agnieszka Czechowicz
- Leveraging Digital Health Solutions to Collect Patient-Reported Outcomes in Rectal Cancer · University of California, San Francisco
Cardiovascular (85 active studies)
- Naloxone for Opioid Associated Out of Hospital Cardiac Arrest · Phase 2 · University of California, San Francisco
- Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease · Phase 2 · Tectonic Operating Company, Inc.
Neurology & pain (84 active studies)
- Alzheimer's Tau Platform: Regimen A - AADvac1 · Phase 2 · Paul S. Aisen
- An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service · Phase 3 · University of California, San Francisco
Mental health & behavior (47 active studies)
- LIFU Effects & Outcomes: Mechanisms Evaluating Striatal Systems Imaging (LEO MESSI) · University of California, San Francisco
- Facilitating Transition to Recommended PTSD Treatment · VA Office of Research and Development
HIV / STI (46 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- Psilocybin Therapy for Methamphetamine Use Disorder and HIV · Phase 2 · Nicky Mehtani, MD, MPH
Diabetes & metabolic (38 active studies)
- PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study · Phase 3 · University of Florida
- Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese · Phase 2 · Biomed Industries, Inc.
Pediatric (21 active studies)
- Prenatal Transplantation for Fetuses With Fanconi Anemia · Phase 1, Phase 2 · Agnieszka Czechowicz
- Music Therapy for Oral Mucositis Pain in Pediatric Patients · University of California, San Francisco
Eye & vision (18 active studies)
- Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center · University of California, San Francisco
- Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes · University of California, San Francisco
Vaccines (13 active studies)
- Validation of Biomarkers for Long COVID in the LIINC Viral Immunopathogenesis and Persistence Repeat Donor Cohort (VIPER) · University of California, San Francisco
- Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC) · EARLY_Phase 1 · University of California, Davis
Common conditions studied in San Francisco
- Breast Cancer (27 active studies)
- Prostate Cancer (27 active studies)
- Heart Failure (18 active studies)
- HIV (15 active studies)
- Cancer (13 active studies)
- Glioblastoma (12 active studies)
Leading research sponsors in San Francisco
- University of California, San Francisco
- Power Life Sciences Inc.
- National Cancer Institute (NCI)
- Children's Oncology Group
- Merck Sharp & Dohme LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in San Francisco?
There are approximately 1,328 recruiting clinical trials in San Francisco, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Francisco pay participants?
Most recruiting trials in San Francisco compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Francisco?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Francisco?
The most common conditions under active study in San Francisco include Breast Cancer (27), Prostate Cancer (27), Heart Failure (18), HIV (15), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Francisco?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Francisco on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Francisco?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Francisco?
Recruiting research sites in San Francisco include University of California, San Francisco, University of California San Francisco, Power Life Sciences, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Francisco right now?
The largest active categories in San Francisco are Cancer & tumors (392), Cardiovascular (85), Neurology & pain (84). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.