Bevacizumab (Avastin) and RAD001(Everolimus)in the Treatment of Advanced Clear Cell Renal Carcinoma

Part of paid clinical trials in Fort Myers, Florida.

Sponsor
SCRI Development Innovations, LLC
Study ID
NCT00323739
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • bevacizumab — DRUG
    Bevacizumab 10mg/kg, IV infusion, every 2 weeks
  • RAD001 — DRUG
    RAD001 10 mg by mouth daily

Study Details

This phase II trial will evaluate the combination of bevacizumab + RAD001 in patients with metastatic renal cell carcinoma. In this trial the investigators will evaluate this combination in patients previously untreated with any anti-angiogenesis agent and patients who have previously received one prior regimen containing an anti-angiogenesis agent.

Key Dates

First listed
May 9, 2006
Start date
May 31, 2006
Status verified
Jul 2013
Primary completion
Nov 30, 2008
Completion
Mar 31, 2011

Study Design

Enrollment
80 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Bevacizumab and RAD001
    Bevacizumab 10mg/kg, IV infusion, every 2 weeks RAD001 10 mg by mouth daily

Primary Outcome Measure

Progression Free Survival (PFS), the Length of Time, in Months, That Patients Were Alive From Their First Date of Protocol Treatment Until Worsening of Their Disease [ Time Frame: 18 months ]

Locations (12)

FacilityCityStateZIPSite coordinators
Florida Cancer SpecialistsFort MyersFlorida33901-
Gainsville Hematology Oncology AssociatesGainesvilleFlorida32605-
Integrated Community Oncology NetworkJacksonvilleFlorida32256-
Florida Hospital Cancer InstituteOrlandoFlorida32804-
Wellstar Cancer ResearchMariettaGeorgia30060-
Consultants in Blood Disorders and CancerLouisvilleKentucky40207-
Baton Rouge General Medical CenterBaton RougeLouisiana70806-
Grand Rapids Clinical Oncology ProgramGrand RapidsMichigan49503-
Methodist Cancer CenterOmahaNebraska68114-
Oncology Hematology CareCincinnatiOhio45242-
Chattanooga Oncology Hematology AssociatesChattanoogaTennessee37404-
Tennessee Oncology, PLLCNashvilleTennessee37023-

Find similar trials in Fort Myers, FL

By condition
Kidney cancer
By specialty
OncologyUrology
By research site
Florida Cancer Specialists· Fort Myers, FLGainsville Hematology Oncology Associates· Gainesville, FLIntegrated Community Oncology Network· Jacksonville, FLFlorida Hospital Cancer Institute· Orlando, FLWellstar Cancer Research· Marietta, GAConsultants in Blood Disorders and Cancer· Louisville, KY

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