Treatment of Acute Lymphoblastic Leukemia (ALL) in Younger Adults

Sponsor
Assistance Publique - Hôpitaux de Paris
Study ID
NCT00327678
Phase
PHASE3
Status
Completed

Conditions

  • Leukemia, Lymphocytic

Eligibility Criteria

Sex
ALL
Age
18 Years - 59 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

This study is a multicenter trial of treatment for young ALL patients. All ALL patients will receive the same steroid pre-phase in order to evaluate sensitivity or resistance. Then, patients will be included into 3 specific trials according to biological features (immunophenotype, cytogenetics, and molecular biology). Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) 2005: * T ALL or B ALL non Ph (N=810 patients planned). * GRAALL 2005 R: B ALL non Ph CD20+ (N=220 patients planned). * GRAAPH 2005: ALL Ph+ (N=270 patients planned)

Key Dates

Start date
May 31, 2006
Status verified
Mar 2016
Primary completion
Apr 30, 2014
Completion
Apr 30, 2014

Study Design

Enrollment
1,080 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Primary Outcome Measure

Event free survival for all patients [ Time Frame: January 2014 ]

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