A Study of Dulanermin Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previously Untreated, Locally Advanced, Recurrent, or Metastatic Colorectal Cancer
Part of paid clinical trials in Los Angeles, California.
- Sponsor
- Genentech, Inc.
- Study ID
- NCT00873756
- Phase
- PHASE1
- Status
- Completed
Conditions
- Metastatic Colorectal Cancer
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- FOLFOX regimen — DRUGIntravenous repeating dose
- bevacizumab — DRUGIntravenous repeating dose
- dulanermin — DRUGIntravenous repeating dose
Study Details
This is a multicenter, open-label study enrolling a total of up to 23 patients.
Key Dates
- First listed
- Apr 2, 2009
- Start date
- May 31, 2009
- Status verified
- Nov 2016
- Primary completion
- Mar 31, 2014
- Completion
- Apr 30, 2014
Study Design
- Enrollment
- 23 participants (actual)
- Allocation
- NON_RANDOMIZED
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: A
Primary Outcome Measure
Incidence and nature of dose-limiting toxicities [ Time Frame: Until study discontinuation or the end of Cycle 26 ]
Locations (7)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| - | Los Angeles | California | 90095 | - |
| - | San Francisco | California | 94115 | - |
| - | Aurora | Colorado | 80045 | - |
| - | Fort Collins | Colorado | 80528 | - |
| - | Harvey | Illinois | 60426 | - |
| - | Albuquerque | New Mexico | 87131 | - |
| - | Chapel Hill | North Carolina | 27599 | - |
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