Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Eylea for Central Retinal Vein Occlusion (CRVO)
- Sponsor
- Bayer
- Study ID
- NCT02040220
- Status
- Completed
Conditions
- Retinal Vein Occlusion
Eligibility Criteria
- Sex
- ALL
- Age
- N/A - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321) — DRUG2 mg of Eylea will be treated per one injection at more than one months interval usually.
Study Details
This is a prospective, non-interventional, multi center post-authorization safety study that includes patients with a diagnosis of CRVO. The investigator will have made the choice of treatment (EYLEA) as well as the decision to use EYLEA according the Japanese Package Insert prior to enrolling the patient in this study. The observation period for each patient starts when therapy with EYLEA is initiated. The enrollment period is 2 years. Patients will be followed for a time period of 2 years or until it is no longer possible (e.g. lost to follow-up) within the 2 years. For each patient, data are collected as defined in the case report form at the initial visit, follow-up visits and final visit, either by routine clinical visits (as per investigators routine practice). There will interim analysis of study data: 6 months after last patient first visit and J-PSUR(Japanese-Periodic Safety Update Report )
Key Dates
- Start date
- Jan 24, 2014
- Status verified
- Apr 2019
- Primary completion
- Jun 1, 2018
- Completion
- Nov 9, 2018
Study Design
- Enrollment
- 385 participants (actual)
Arms
- Arm: Group 1Eylea treatment goup
Primary Outcome Measure
Number of episodes of adverse drug reactions and adverse events(serious or non-serious, related or not related, ocular or non ocular) [ Time Frame: 6 months after start of treatment with the drug ]
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