Efficacy and Safety of Evoglitin in Patients With Type 2 Diabetes and Non-alcoholic Fatty Liver Diseases
- Sponsor
- Dong-A ST Co., Ltd.
- Study ID
- NCT03910361
- Phase
- PHASE4
- Status
- Completed
Conditions
- Non-Alcoholic Fatty Liver Disease
- Type2 Diabetes
Eligibility Criteria
- Sex
- ALL
- Age
- 19 Years - 70 Years
- Healthy Volunteers
- Not accepted
Interventions
- Evogliptin — DRUGevogliptin 5mg tablet qd + placebo tablet matching to pioglitazone 15mg qd
- Pioglitazone — DRUGpioglitazone 15mg tablet qd + placebo tablet matching to evogliptin 5mg qd
Study Details
A multicenter, double-blind, active-controlled, randomized, parallel, phase IV clinical trial to evaluate the efficacy and safety of evogliptin in patients with type 2 diabetes and non-alcoholic fatty liver diseases
Key Dates
- First listed
- Apr 10, 2019
- Start date
- Apr 12, 2019
- Status verified
- Apr 2021
- Primary completion
- Jul 2, 2020
- Completion
- Jul 2, 2020
Study Design
- Enrollment
- 51 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: Evogliptinevogliptin 5mg
- Active Comparator: Pioglitazonepioglitazone 15mg
Primary Outcome Measure
Changes from baseline intrahepatic fat (%) [ Time Frame: 24 weeks ]
Related Studies
- A Causative Role for Amylin in Diabetic Peripheral NeuropathyRecruiting · Zabeen Mahuwala, MD · Lexington, Kentucky
- SGLT2 Inhibitors as a Novel Treatment for Pediatric Non-Alcoholic Fatty Liver DiseasePHASE2 · Not Yet Recruiting · Justin Ryder · Chicago, Illinois
- Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)PHASE2 · Recruiting · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Bethesda, Maryland
- Uric Acid Lowering Trial in Youth Onset T2DPHASE2 · Recruiting · University of Colorado, Denver · Aurora, Colorado