Microwave Ablation in Combination With Camrelizumab Versus Camrelizumab in Metastatic Non-small-cell Lung Cancer
- Sponsor
- Shandong Provincial Hospital
- Study ID
- NCT04102982
- Phase
- PHASE2
- Status
- Unknown
Conditions
- NSCLC Stage IV
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- Camrelizumab — DRUGPatients will be treated with camrelizumab alone.
- Camrelizumab plus microwave ablation — OTHERIn the group, microwave ablation will be administrated to the primary tumors, followed by camrelizumab.
Study Details
Patients were randomized to microwave ablation plus camrelizumab group or camrelizumab group.
Key Dates
- Start date
- Nov 1, 2019
- Status verified
- Oct 2020
- Primary completion
- Oct 31, 2021
- Completion
- Feb 28, 2022
Study Design
- Enrollment
- 200 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- OTHER
Arms
- Active Comparator: Microwave ablation plus camrelizumab groupPatients in the group are treated with Microwave ablation in the primary tumor, followed by camrelizumab.
- Placebo Comparator: Camrelizumab groupPatients in the group are treated with camrelizumab alone.
Primary Outcome Measure
Objective response rate [ Time Frame: The proportion of Patients achieved complete response or partial response up to 16 weeks ]
Central Contacts
- Xin Ye+8653168773171
- Zhigang Wei+8653168773171
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