ICONIC: Improving Outcomes Through Collaboration in OsteosarComa

Sponsor
University College, London
Study ID
NCT04132895
Status
Recruiting
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Conditions

  • Osteosarcoma

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • observational only, no interventions are prescribed in protocol. — OTHER
    * Treatment will be given as per usual standard of care. * No treatments are specified by this protocol.

Study Details

There has been little improvement in outcome for patients with osteosarcoma (OS) over the last 20 years. There have been only a few clinical trials of new treatments and no major new therapies introduced recently. This is in part because there is no good understanding of the biology of osteosarcoma, but also trials have only included subgroups of patients. The more that is understood about how and why osteosarcoma arises and grows the better clinicians will be able to decide what treatments are most likely to work best. The purpose of this project is to collect high quality clinical data about patients of all ages with osteosarcoma, such as information about the size of the disease, how it was diagnosed and where it is at diagnosis, what treatments were given and how the disease responded the treatments. Blood and tissue samples will also be collected for analysis in research laboratories. By looking at the results of the laboratory findings and the clinical data together, the questions will start to be answered about why osteosarcomas arise and grow, what makes it spread, and why some patients respond to treatment better than others. As time goes on, this information is planned to be used to develop clinical trials of new treatments. Alongside this, the aim is to find out more about how osteosarcoma and its treatments affect the lives of those living with this disease. This information will help provide the most appropriate care and support that will meet the needs of each patient. Ultimately, the aim is to improve the care and treatment of osteosarcoma patients so that they may live longer and better lives.

Key Dates

First listed
Oct 21, 2019
Start date
Oct 25, 2019
Status verified
Jul 2024
Primary completion
Jan 31, 2025
Completion
Jan 31, 2027

Study Design

Enrollment
300 participants (estimated)

Primary Outcome Measure

Feasibility phase: Patient recruitment. [ Time Frame: One year from study opening. ]

Central Contacts

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