Clinical Translation of a Novel Brain PET Insert for Simultaneous PET/MR

Part of paid clinical trials in Palo Alto, California.

Sponsor
Stanford University
Study ID
NCT04383808
Status
Recruiting
Apply to this trial

Conditions

  • Brain Disease

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Injected radiotracer with PET Insert — DIAGNOSTIC_TEST
    1. Informed consent will be obtained before beginning any study procedures. 2. Participants will receive a small quantity of an FDA approved radiotracer. The PET insert is placed within a 3T MRI scanner, where PET and MRI imaging will be completed.
  • Pre-injected group with PET insert — DIAGNOSTIC_TEST
    1. Informed consent will be obtained before beginning any study procedures. 2. Participants who have received radiotracer for another PET imaging system. The PET insert is placed within a 3T MRI scanner, where PET and MRI imaging will be completed.

Study Details

The primary goal of this project is to study the feasibility of a brain-dedicated PET insert for an MR scanner for simultaneous acquisition of PET/MR images of human brains. The study will also allow us to compare the imaging performance of the investigator's brain-dedicated PET insert against a commercial whole-body permanently integrated PET/MRI system using a common radiopharmaceutical.

Key Dates

First listed
May 12, 2020
Start date
Apr 1, 2025
Status verified
Apr 2025
Primary completion
Mar 31, 2027
Completion
Mar 31, 2028

Study Design

Enrollment
40 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Arm-1
    20 participants will be recruited, inject with radiopharmaceutical, and imaged on the 3T PETMR with PET insert.
  • Experimental: Arm-2
    20 participants will be recruited from other imaging studies that have been already injected (pre-injected) with a radiopharmaceutical. These subjects wont receive an additional injection of radiopharmaceutical.

Primary Outcome Measure

PETMR image [ Time Frame: Up to 24 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Stanford UniversityPalo AltoCalifornia94305
Paul Newswanger, MPH
[email protected]
650-736-1349

Find similar trials in Palo Alto, CA

By research site
Stanford University· Palo Alto, CA

Related Studies