Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech

Sponsor
Karolinska Institutet
Study ID
NCT04604444
Status
Recruiting
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Conditions

  • Aphasia
  • Apraxia of Speech
  • Dysarthria

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Multimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech — BEHAVIORAL
    Intensive Comprehensive Aphasia (ICAP) and Apraxia of Speech Program

Study Details

The present study aims to investigate the short- and long-term effects of two weeks of intensive speech-language pathology intervention with additional physiotherapy, on aphasia and apraxia of speech (AOS) and their neural correlates in thirty persons with chronic stroke. Changes are studied following intensive treatment of aphasia and AOS with standardised speech-language testing and testing of communication and with voxel-based morphometry (VBM) analysis and resting state functional connectivity (rsFC).

Key Dates

First listed
Oct 27, 2020
Start date
Feb 2, 2017
Status verified
Oct 2024
Primary completion
Dec 31, 2026
Completion
Dec 31, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Multimodal Intensive Rehabilitation of Aphasia/AOS (MIRAA)
    A minimum of 3 hour speech-language training daily during 10 days.

Primary Outcome Measure

Comprehensive Aphasia Test (CAT) language battery, in pilot Swedish test A-ning. [ Time Frame: Changes from baseline in language battery scores at 2 and 18 weeks. ]

Central Contacts

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