Tocilizumab and Cytokine Release Syndrome (CRS) In Covid-19 Pneumonia
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
- Study ID
- NCT04873141
- Status
- Completed
Conditions
- Covid-19 Pneumonia
- Cytokine Release Syndrome
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Tocilizumab 200 Mg/10 mL (20 Mg/mL) INTRAVEN VIAL (ML) — DRUGTocilizumab was given according to weight in patients with cytokinme releasew syndrome (CRS).
Study Details
Tocilizumab (TCZ), interleukin-6 (IL-6), newly appeared as treatment of cytokine release syndrome (CRS) in patients with severe covid-19 associated pneumonia. In the present study, we aimed to discuss the treatment response of TCZ therapy in COVID-19 infected patients.
Key Dates
- Start date
- Apr 28, 2020
- Status verified
- May 2021
- Primary completion
- Jun 22, 2020
- Completion
- Jun 22, 2020
Study Design
- Enrollment
- 24 participants (actual)
Arms
- Arm: Case GroupAll the patients suffering from severe covid pneumonia and laboratory parameter suggestive of cytokine release syndrome.
Primary Outcome Measure
Mortality Rate [ Time Frame: 28 days ]
Related Studies
- Cardiac Magnetic Resonance Tissue Characterization in COVID-19 SurvivorsRecruiting · Weill Medical College of Cornell University · Brooklyn, New York
- Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell TherapyPHASE1/PHASE2 · Recruiting · CytoAgents, Inc. · Orange, California
- Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational MedicineRecruiting · The Geneva Foundation · Fort Sam Houston, Texas
- Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to EpcoritamabPHASE1 · Recruiting · Taylor Brooks · Cleveland, Ohio