Predictive Biomarkers in Patients With Advanced Hepatocellular Carcinoma Treated With Atezolizumab Plus Bevacizumab
- Sponsor
- CHA University
- Study ID
- NCT05173298
- Status
- Unknown
Conditions
- Advanced Hepatocellular Carcinoma
Eligibility Criteria
- Sex
- ALL
- Age
- 19 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- atezolizumab plus bevacizumab — DRUG1200 mg of atezolizumab plus 15 mg/kg of body weight of bevacizumab intravenously every 3 weeks
Study Details
The goal of this observational study is to learn about in patients with advanced hepatocellular carcinoma treated with atezoliozumab and bevacizumab. In this clinical study, we intend to analyze the multiomics data by analyzing the peripheral blood and tumor tissue before and after treatment of patients with advanced liver cancer receiving systemic drug treatment, and analyzing the correlation with the treatment. This is an exploratory study that aims to discover biomarkers that are highly correlated with treatment response.
Key Dates
- Start date
- Aug 2, 2021
- Status verified
- Feb 2024
- Primary completion
- Jul 31, 2024
- Completion
- Dec 31, 2024
Study Design
- Enrollment
- 100 participants (estimated)
Arms
- Arm: analytic groupadvanced HCC Patients
Primary Outcome Measure
collected tumor samples [ Time Frame: through study completion, an average of 3 years ]
Central Contacts
- Hong Jae Chon, MD,PhD82-031-780-3928
Related Studies
- Durvalumab With/Without Tremelimumab After Palliative Hypofractionated Radiotherapy for Hepatocellular CarcinomaPHASE2 · Recruiting · Mary Feng, MD · San Francisco, California
- Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or ThoraxPHASE1 · Recruiting · M.D. Anderson Cancer Center · Houston, Texas
- AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic DiseasePHASE1 · Recruiting · University of Southern California · Los Angeles, California
- A Study of Tegavivint (BC2059) in Patients With Advanced Hepatocellular CarcinomaPHASE1/PHASE2 · Recruiting · Iterion Therapeutics · Duarte, California