Multiparametric Assessment of Bone Response in mCRPC Patients Treated With Cabozantinib

Sponsor
Alfredo Berruti
Study ID
NCT05265988
Phase
PHASE2
Status
Completed

Conditions

  • Carcinoma Prostate

Eligibility Criteria

Sex
MALE
Age
N/A - N/A
Healthy Volunteers
Accepted

Interventions

  • Cabozantinib — DRUG
    Cabozantinib at initial dosage of 40 mg per day and continuation of androgen deprivation therapy

Study Details

Multiparametric assesment of bone response in mCRPC patients treated with Cabozantinib upon progression to chemotherapy and next generation hormonal agents: a phase II study

Key Dates

Start date
Nov 29, 2021
Status verified
Jul 2024
Primary completion
Jun 29, 2024
Completion
Jun 29, 2024

Study Design

Enrollment
32 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Meridian
    Cabozantinib at initial dosage of 40 mg per day and continuation of androgen deprivation therapy

Primary Outcome Measure

Objective response rate (ORR) on bone metastases through whole body diffusione weighted (WB-DW) MRI. [ Time Frame: 6 months ]