Biomarkers in Autoimmune Diseases, Vasculitis and Auto Inflammatory Diseases

Sponsor
Assistance Publique - Hôpitaux de Paris
Study ID
NCT05383339
Status
Recruiting
Apply to this trial

Conditions

  • Autoimmune Diseases
  • Autoinflammatory Disease
  • Vasculitis

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Blood collection — OTHER
    \- 56mL blood collected additionally to routine care

Study Details

The objective of this work is to identify, in patients with autoimmune diseases, systemic vasculitis and autoinflammatory disease, cytokine and lymphocyte biomarkers of activity of these diseases to identify follow-up biomarkers, in order to personalize the follow-up and the treatments for each patient. Immunological data will be obtained from biological samples collected as part of the usual patient care pathway (Blood and tissues sampling) The study will take place in the Department of Internal Medicine and Clinical Immunology (DMIIC), that is certified as the National Reference Centre for Rare Systemic Autoimmune Diseases and the National Reference Centre for Inflammatory Autoinflammatory Diseases and Inflammatory Amyloidosis (CEREMAIA). Its objective is to contribute to the advancement of fundamental knowledge in immunology, in particular to develop prognostic biomarkers of the activity of autoimmune diseases, systemic vasculitis and autoinflammatory diseases by using blood tests.

Key Dates

Start date
Nov 29, 2022
Status verified
Jun 2025
Primary completion
Nov 29, 2031
Completion
Nov 29, 2031

Study Design

Enrollment
2,250 participants (estimated)

Arms

  • Arm: Patients
    Patients with autoimmune diseases, vasculitis and autoinflammatory diseases

Primary Outcome Measure

Correlation between cytokine and lymphocyte profile and disease activity [ Time Frame: through study completion, an average of 9 years ]

Central Contacts

Related Studies