Optimizing Protein Patterns for Skeletal Muscle Preservation and Sleep in the Medical Management of Parkinson Disease

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
University of Alabama at Birmingham
Study ID
NCT05437640
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
45 Years - 99 Years
Healthy Volunteers
Not accepted

Interventions

  • Protein Redistribution Diet — BEHAVIORAL
    PD participants will be instructed by a Registered Dietitian to consume 10 grams or less of protein until their evening meal. They will then consume a high protein evening meal to meet their protein needs. They will receive one-on-one education and supportive materials to follow diet plan.
  • Protein Consistent Diet — BEHAVIORAL
    PD participants will be instructed by a Registered Dietitian to consume 20-30 grams of protein per meal. They will receive one-on-one education and supportive materials to follow diet plan.

Study Details

The purpose of this pilot study is to generate preliminary data on the impact of the dietary protein pattern on markers of skeletal muscle health and drug efficacy in Parkinson disease.

Key Dates

Start date
Oct 1, 2022
Status verified
Jun 2025
Primary completion
Nov 25, 2024
Completion
Nov 25, 2024

Study Design

Enrollment
12 participants (actual)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Active Comparator: Protein Redistribution Diet
    PD participants may first be randomized to follow the Protein Redistribution Diet followed by the Protein Consistent Diet.
  • Active Comparator: Protein Consistent Diet
    PD participants may first be randomized to follow the Protein Consistent Diet followed by the Protein Redistribution Diet.

Primary Outcome Measure

Change in Markers of Skeletal Muscle Metabolism GDF15 [ Time Frame: Baseline to 5 weeks ]

Locations (1)

FacilityCityStateZIP
University of Alabama at BirminghamBirminghamAlabama35233

Find similar trials in Birmingham, AL

By condition
Parkinson's disease
By specialty
NeurologyBrain disorders
By research site
University of Alabama at Birmingham· Birmingham, AL

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