Paid Clinical Trials in Birmingham, AL
As of September 2026, 1,016 paid clinical trials are recruiting in Birmingham, Alabama. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Birmingham offers studies at sites including University of Alabama at Birmingham for conditions such as Obesity, Breast Cancer, Hypertension, Ovarian Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Birmingham
Trials by drug in Birmingham
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Newly added in Birmingham
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
A Study to Assess the Efficacy and Safety of GIA632 Across a Range of Doses in Participants With Moderate to Severe Cutaneous Lichen Planus
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy
872 clinical trials
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
A Study of Buntanetap in Participants With PD
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
A Study of Dotinurad Versus Allopurinol in Participants With Gout
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
Top Research Study Locations in Birmingham
Researchers run research studies in Birmingham, AL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Alabama at Birmingham | Hypertension, Cancer, Cardiovascular Diseases | 349 |
| Children's Hospital of Alabama | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm | 38 |
| University of Alabama at Birmingham Cancer Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Recurrent Endometrial Carcinoma | 35 |
| University of Alabama | Chronic Kidney Disease(CKD), Type 2 DM, Type 2 Diabetes Mellitus (T2DM) | 32 |
| University of Alabama Birmingham | Amyotrophic Lateral Sclerosis, AML (Acute Myelogenous Leukemia), Acetabulum Fractures | 29 |
| The University of Alabama at Birmingham | Idiopathic Pulmonary Fibrosis, ALK-positive Histiocytosis, Aging | 28 |
| UAB | Opioid Overdose, Opioid Use Disorder, Alzheimer Disease | 15 |
| Children's of Alabama | Acute Kidney Injury, Acute Kidney Injury Due to Sepsis, Bowel Incontinence | 15 |
| University of Alabama Hospital | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 13 |
| Birmingham VA Medical Center, Birmingham, AL | Adult Growth Hormone Deficiency, Aging, Carcinoma, Hepatocellular | 11 |
| University of Alabama - Birmingham | Obstetrical Complications, Acute Myeloid Leukemia, CPPD - Calcium Pyrophosphate Deposition Disease | 8 |
| University of Alabama At Birmingham Hospital | Advanced Solid Tumor, Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma | 7 |
| Alabama Oncology | Non-Small Cell Lung Cancer, Cancer, Hormone Receptor Positive HER-2 Negative Breast Cancer | 6 |
| University of Alabama, Birmingham | Acute Porphyrias, Alzheimer's Disease (AD), Bone Marrow Transplant (BMT) | 6 |
| AllerVie Clinical Research | Atopic, Atopic Dermatitis, Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) | 6 |
| Central Research Associates | Chronic Pain, Osteoarthritis, Knee, Chronic Low-back Pain | 5 |
| Univ of Alabama Birmingham | Obesity, Heart Failure, Overweight | 5 |
| Alabama Clinical Therapeutics | Degenerative Disc Disease, Degenerative Disc Disease (DDD), Growth | 4 |
| Clinical Trial Site | Acute Hepatic Porphyria, Generalized Myasthenia Gravis, High Cardiovascular Risk | 4 |
| Birmingham Clinical Research | Obesity, Overweight, Atherosclerotic Cardiovascular Disease (ASCVD) | 4 |
| Central Alabama Research | Colorectal Cancer, Early Breast Cancer, Influenza | 4 |
| O'Neal Comprehensive Cancer Center at UAB | Advanced Lung Carcinoma, Carcinoma, Endometrial Cancer | 4 |
| The Children's Hospital Alabama, University of Alabama at Birmingham | Cystic Fibrosis, Cystic Fibrosis (CF), Cystic Fibrosis Pulmonary Exacerbation | 4 |
| The Kirklin Clinic | Breast Cancer, Breast Neoplasm, Cancer | 4 |
| The Kirklin Clinic of UAB Hospital | Cachexia, Chronic Myelomonocytic Leukemia, Gout | 4 |
Active & Upcoming Studies in Birmingham (2026)
Recruiting trials in Birmingham grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (237 active studies)
- Developing Pilot Postoperative Guidelines for Improved Functional Outcomes After High-Risk Cancer Surgery · University of Alabama at Birmingham
- Monitoring Breast Cancer Immunotherapy Treatment With Advanced Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI) · EARLY_Phase 1 · University of Alabama at Birmingham
Cardiovascular (64 active studies)
- Monitoring Blood Pressure at Home and Pharmacy Telehealth · University of Alabama at Birmingham
- Feasibility and Acceptability of Three Component Intervention for the Heart Failure Care for Rural Dwelling Participants · University of Alabama at Birmingham
Diabetes & metabolic (62 active studies)
- MEDBRIDGE-Guided NCM/CHW Post-Discharge Support for High-Risk T2D Patients · University of Alabama at Birmingham
- Semaglutide for Low Back Pain · Phase 2 · Washington University School of Medicine
Neurology & pain (59 active studies)
- Semaglutide for Low Back Pain · Phase 2 · Washington University School of Medicine
- Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis · University of Alabama at Birmingham
Pediatric (24 active studies)
- Application to Predict Neonatal Apnea With Bradycardia · University of Alabama at Birmingham
- Video Inspired Discussions About Ethical Outcomes in Pediatrics · Massachusetts General Hospital
HIV / STI (22 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- A Clinical Study to Evaluate the Safety and Immunogenicity of a Higher Dose of the Study Vaccine, VIR-1388, in HCMV-seropositive Adult Participants Without HIV · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Mental health & behavior (21 active studies)
- Mobile Thinking Intervention: A Inital Test · University of Alabama at Birmingham
- A Cognitive Mobile Intervention for Motivation in Psychotic Disorders · Phase 1, Phase 2 · University of Alabama at Birmingham
Vaccines (12 active studies)
- How Healthy Adults Respond to the Nasal Flu Vaccine · Phase 4 · University of Alabama at Birmingham
- Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines · Phase 4 · University of Alabama at Birmingham
Eye & vision (5 active studies)
- Integrative Liver-Targeted Therapy for Diabetic Macular Edema: Using "Tauroursodeoxycholate" or Traditional Chinese Medicine. · Phase 2 · University of Alabama at Birmingham
- Intranasal Delivery of Octreotide for Treatment of Diabetic Macular Edema · Phase 1 · University of Alabama at Birmingham
Common conditions studied in Birmingham
- Obesity (19 active studies)
- Breast Cancer (15 active studies)
- Hypertension (13 active studies)
- Cancer (12 active studies)
- Ovarian Cancer (12 active studies)
- Overweight (12 active studies)
Leading research sponsors in Birmingham
- University of Alabama at Birmingham
- National Cancer Institute (NCI)
- Children's Oncology Group
- AstraZeneca
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Birmingham?
There are approximately 1,016 recruiting clinical trials in Birmingham, Alabama listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Birmingham pay participants?
Most recruiting trials in Birmingham compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Birmingham?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Birmingham?
The most common conditions under active study in Birmingham include Obesity (19), Breast Cancer (15), Hypertension (13), Cancer (12), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Birmingham?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Birmingham on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Birmingham?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Birmingham?
Recruiting research sites in Birmingham include University of Alabama at Birmingham, Children's Hospital of Alabama, University of Alabama at Birmingham Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Birmingham right now?
The largest active categories in Birmingham are Cancer & tumors (237), Cardiovascular (64), Diabetes & metabolic (62). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.