SV2A in Older Adults

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Yale University
Study ID
NCT05465538
Phase
PHASE1/PHASE2
Status
Recruiting
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Conditions

  • Cannabis Use

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • [11C]UCB-J PET — DRUG
    Single PET scan using the radioligand \[11C\]UCB-J

Study Details

The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using \[11C\]UCB-J PET imaging.

Key Dates

First listed
Jul 19, 2022
Start date
Jul 6, 2022
Status verified
Feb 2026
Primary completion
Dec 30, 2026
Completion
Sep 30, 2027

Study Design

Enrollment
24 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Other: Cannabis using older adults
    Subjects undergo a single PET scan using \[11C\]UCB-J
  • Other: Healthy controls
    Subjects undergo a single PET scan using \[11C\]UCB-J

Primary Outcome Measure

Hippocampal synaptic density [ Time Frame: 1 month ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Conneticut Mental Health CenterNew HavenConnecticut06519
Angerlyk Frytz, MD
[email protected]
203-974-7822

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By research site
Conneticut Mental Health Center· New Haven, CT

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