Lowdose Nivolumab in Combination With AVD as Front Line Therapy for Classic Hodgkin's Lymphoma
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
- Study ID
- NCT05772624
- Phase
- PHASE2
- Status
- Unknown
Conditions
- Efficacy, Self
- Safety Issues
Eligibility Criteria
- Sex
- ALL
- Age
- 16 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- low dose nivolumab in combination with AVD — DRUGNivolumab as an standard dose of 40mg in combination with AVD.
Study Details
This study aims to prove the efficacy and safety of low dose nivolumab (40mg as the lowest available presentation) in combination with AVD (adriamycin,vinblastine sulfate and dacarbazine) as frontline treatment for classic Hodgkin's lymphoma.
Key Dates
- Start date
- Feb 13, 2023
- Status verified
- Mar 2023
- Primary completion
- Mar 1, 2024
- Completion
- Jun 1, 2024
Study Design
- Enrollment
- 16 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: LowN-AVDclassic Hodgkin's lymphoma patients receiving low dose nivolumab in combination with AVD
Primary Outcome Measure
To determine general response [ Time Frame: Six weeks after completion of therapy. ]
Central Contacts
- David Gomez Almaguer, MD+52 8183486136
Related Studies
- E-CEL UVEC Cells as an Adjunct Cell Therapy for the Arthroscopic Rotator Cuff Repair in AdultsPHASE1 · Enrolling By Invitation · Hospital for Special Surgery, New York · New York, New York
- Phase1/2a Study for IPG7236 in Patients With Advanced Solid TumorsPHASE1/PHASE2 · Recruiting · Nanjing Immunophage Biotech Co., Ltd · Portland, Oregon
- Pediatric Trauma Centers RE-AIM at Gun SafetyEnrolling By Invitation · Johns Hopkins University · Baltimore, Maryland
- Adult Trauma Centers RE-AIM at Gun SafetyEnrolling By Invitation · Johns Hopkins University · Baltimore, Maryland