ctDNA in CRC Patients Undergoing Curative-intent Surgery for Liver Metastases
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
- Study ID
- NCT05787197
- Status
- Recruiting
Conditions
- Circulating Tumor DNA
- Metastatic Colorectal Cancer
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Study Details
This is a prospective multicenter cohort study, was designed to explore the prognostic value of ctDNA as a biomarker of disease response and recurrence or death in patients undergoing curative-intent surgical resection of Colorectal cancer liver metastasis.
Key Dates
- First listed
- Mar 28, 2023
- Start date
- Jan 9, 2024
- Status verified
- Jul 2025
- Primary completion
- Sep 25, 2025
- Completion
- Jun 30, 2027
Study Design
- Enrollment
- 232 participants (estimated)
Primary Outcome Measure
Disease-free survival (DFS) in patients who undergo curative-intent resection of colorectal liver metastasis (CRLM) [ Time Frame: Up to 36 months ]
Central Contacts
- Maximiliano GELLI, MD+33(0)1 40 29 85 00
- Marie Line GARCIA, MD+33(0)1 40 29 85 00
Related Studies
- Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic CancerPHASE2 · Recruiting · National Cancer Institute (NCI) · Bethesda, Maryland
- Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)PHASE2 · Recruiting · Dana-Farber Cancer Institute · San Francisco, California
- A Study of ART0380 for the Treatment of Advanced or Metastatic Solid TumorsPHASE1/PHASE2 · Recruiting · Artios Pharma Ltd · Birmingham, Alabama
- A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)PHASE1 · Recruiting · Hoffmann-La Roche · Phoenix, Arizona