Prospective Clinical Study of ZPR Regimen in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Sponsor
Peng Liu
Study ID
NCT05940051
Phase
PHASE2
Status
Unknown

Conditions

  • Diffuse Large B Cell Lymphoma

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

This is a prospective, single-arm, single-center clinical study. This clinical study aims to explore the efficacy and safety of the ZPR（Zanubrutinib, Polatuzumab vedotin and Rituximab）regimen in the treatment of patients with relapsed and refractory diffuse large B-cell lymphoma.

Key Dates

Start date
Jul 20, 2023
Status verified
Jul 2023
Primary completion
Jul 1, 2025
Completion
Dec 30, 2025

Study Design

Enrollment
35 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: R/R Diffuse Large B-cell Lymphoma

Primary Outcome Measure

ORR at the end of the 6th treatment cycle [ Time Frame: about six months from the start of ZPR ]

Central Contacts

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