CT Quantitative Assessment of Interstitial Lung Disease

Sponsor
Assiut University
Study ID
NCT05947422
Status
Recruiting
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Conditions

  • Interstitial Lung Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - 90 Years
Healthy Volunteers
Not accepted

Interventions

  • High resolution CT Chest — DIAGNOSTIC_TEST
    CT chest in our institution will be done with standard high resolution protocol . No I.V contrast will be given. Scans will be obtained during full inspiration in supine position from the thoracic inlet to the level of the diaphragm. Patients with CT chest performed outside our institution will be reviewed in DICOM format and assessed for its compatibility to be integrated into the computer-based analysis software.
  • Spirometry — DIAGNOSTIC_TEST
    Spirometry will be performed using standard techniques according to ATS-ERS criteria 2019 . Spirometry device (Zan 300, NSPIRE HEALTH GMBH Co.) will be used. Percentage predicted values (%pred) will be calculated based on reference values for healthy adults. All patients will be required to undergo spirometry in a reproducible way, and the best values will be reported. Spirometry should meet international acceptability and repeatability standards

Study Details

Interstitial lung disease (ILD) refers to a broad category of heterogeneous lung diseases with different etiologies and features characterized by inflammation and fibrosis of the lung parenchyma and manifested as exertional dyspnea, interstitial patterns on high resolution computed tomography (HRCT), and abnormal pulmonary function tests (PFTs) The aim of this study is to investigate is there any correlation between changes seen in the lung parenchyma by HRCT and the pulmonary functions of the patients.

Key Dates

First listed
Jul 17, 2023
Start date
Dec 1, 2023
Status verified
Apr 2025
Primary completion
Dec 1, 2025
Completion
Dec 30, 2025

Study Design

Enrollment
70 participants (estimated)

Primary Outcome Measure

CT visual Warrick score (measured by points) [ Time Frame: baseline ]

Central Contacts

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