Cetuximab in Combination With Dabrafenib and Tislelizumab in BRAF Mutated Treatment of Advanced Colorectal Cancer
- Sponsor
- Zhejiang Cancer Hospital
- Study ID
- NCT05963087
- Status
- Not Yet Recruiting
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Conditions
- Advanced Colorectal Cancer
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Cetuximab Dabrafenib Tislelizumab — DRUGDabrafenib 150mg,BID, Cetuximab 250mg/m2, Tislelizumab 200mg Treatment every three weeks
Study Details
To explore the efficacy and safety of Cetuximab in combination with dabrafenib and Tislelizumab in BRAF mutated treatment of advanced colorectal cancer
Key Dates
- Start date
- Aug 31, 2023
- Status verified
- Jul 2023
- Primary completion
- Feb 28, 2025
- Completion
- Jun 30, 2026
Study Design
- Enrollment
- 22 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Advanced CRCPatients with BRAF Mutated Advanced CRC were given Cetuximab in Combination With Dabrafenib and Tislelizumab
Primary Outcome Measure
Objective response rate (ORR) [ Time Frame: up to 12 months ]
Central Contacts
- Wangxia Lv13757141026
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