NIA_Improving Function and Well-being by Improving Patient Memory: Transdiagnostic Sleep and Circadian Treatment

Part of paid clinical trials in Berkeley, California.

Sponsor
University of California, Berkeley
Study ID
NCT05986604
Status
Recruiting
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Conditions

  • Circadian Dysregulation
  • Memory Impairment
  • Sleep Disorder

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Memory Support Intervention — BEHAVIORAL
    The Memory Support Intervention is designed to improve patient memory for treatment and involves a series of specific procedures that support the encoding and retrieval stages of episodic memory. The memory support strategies are proactively, strategically and intensively integrated into treatment-as-usual to support encoding. Memory support is delivered alongside each 'treatment point', defined as a main idea, principle, or experience that the treatment provider wants the patient to remember or implement as part of the treatment.
  • Transdiagnostic Intervention for Sleep and Circadian Dysfunction — BEHAVIORAL
    TranS-C aims to provide one protocol to treat a range of sleep and circadian problems because sleep and circadian problems are often not so neatly categorized and because the existing research provides few guidelines to treat more complex patients.

Study Details

Mental illness is often chronic, severe, and difficult to treat. Though there has been significant progress towards establishing effective and efficient interventions for psychological health problems, many individuals do not gain lasting benefits from these treatments. The Memory Support Intervention (MSI) was developed utilizing existing findings from the cognitive science literature to improve treatment outcomes. In this study, the investigators aim to conduct an open trial that includes individuals 50 years and older to assess if a novel version of the Memory Support Intervention improves sleep and circadian functioning, reduces functional impairment, and improves patient memory for treatment.

Key Dates

First listed
Aug 14, 2023
Start date
Jan 4, 2024
Status verified
Nov 2025
Primary completion
Feb 28, 2028
Completion
Jul 28, 2028

Study Design

Enrollment
178 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: TranS-C+MSI
    Transdiagnostic Intervention for Sleep and Circadian Dysfunction will be combined with the Memory Support Intervention
  • Active Comparator: TranS-C alone
    The Transdiagnostic Sleep and Circadian Intervention will be delivered alone

Primary Outcome Measure

Patient-Reported Outcomes Measurement Information System - Sleep Disturbance [ Time Frame: Change from baseline to post-treatment, which is 8-10 weeks after the beginning of treatment to 6-month follow-up to 12-month follow-up ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, BerkeleyBerkeleyCalifornia94720-1650
Allison Harvey, PhD
[email protected]
510-642-7138
Nena Salazar
[email protected]
‪(925) 421-0083‬

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By research site
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