A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

Part of paid clinical trials in Duarte, California.

Sponsor
CRISPR Therapeutics AG
Study ID
NCT06208878
Status
Enrolling By Invitation

Conditions

  • Hematologic Malignancy
  • Solid Malignancy

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Non Interventional — OTHER
    Safety and Efficacy Assessment

Study Details

This study will evaluate the long-term safety and efficacy of CRISPR CAR T cellular therapies

Key Dates

First listed
Jan 17, 2024
Start date
Nov 22, 2023
Status verified
Aug 2025
Primary completion
Aug 31, 2038
Completion
Aug 31, 2038

Study Design

Enrollment
70 participants (estimated)

Arms

  • Arm: Non Interventional
    All subjects with hematological and solid malignancies who are enrolled in a parent study and were exposed to allogeneic CRISPR CAR T cellular therapy will be asked to participate in this long-term follow-up (LTFU) study.

Primary Outcome Measure

The incidence of adverse events, serious adverse events and adverse events of special interest related to CRISPR CAR T cellular therapy treatment. [ Time Frame: 15 years ]

Locations (17)

FacilityCityStateZIPSite coordinators
City of HopeDuarteCalifornia91010-
Cedars SinaiLos AngelesCalifornia90048-
StanfordStanfordCalifornia94305-
Yale New Haven HospitalNew HavenConnecticut06510-
EmoryAtlantaGeorgia30322-
University of ChicagoChicagoIllinois60637-
University of KansasWestwoodKansas66205-
University of MinnesotaMinneapolisMinnesota55455-
Washington University Saint LouisSt LouisMissouri63110-
MSKCCNew YorkNew York10065-
Montefiore Medical CenterThe BronxNew York10467-
Oregon Health and Science UniversityPortlandOregon97239-
University of PennsylvaniaPhiladelphiaPennsylvania19104-
UT SouthwesternDallasTexas75390-
MD Anderson Cancer CenterHoustonTexas77030-
Methodist Hospital-Sarah CannonSan AntonioTexas78229-
University of Utah-Huntsman Cancer InstituteSalt Lake CityUtah84112-

Find similar trials in Duarte, CA

By research site
City of Hope· Duarte, CACedars Sinai· Los Angeles, CAStanford· Stanford, CAYale New Haven Hospital· New Haven, CTEmory· Atlanta, GAUniversity of Chicago· Chicago, IL

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