Functional and Phenotypic Characterization of Monocytes in Myeloproliferative Syndromes

Sponsor
University Hospital, Angers
Study ID
NCT06361641
Status
Recruiting
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Conditions

  • Essential Thrombocythemia
  • Myeloproliferative Neoplasm
  • Polycythemia Vera
  • Primary Myelofibrosis

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Monocytes signatures in myeloproliferative neoplasms at diagnosis — DIAGNOSTIC_TEST
    The monocytes signatures will be perform from a peripheral blood sample. The signature will be derived from (i) surface marker expression, (ii) cytokines profiles, (iii) genes expression.

Study Details

Prospective study for functional and phenotypic characterization of monocytes in philadelphia-negative myeloproliferative neoplasms

Key Dates

First listed
Apr 12, 2024
Start date
May 29, 2024
Status verified
Dec 2025
Primary completion
Oct 19, 2026
Completion
Oct 19, 2028

Study Design

Enrollment
70 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: Phemop Cohort

Primary Outcome Measure

WHO 2016 criteria for polycythemia vera, prefibrotic myelofibrosis, essential thrombocytosis and overt myelofibrosis diagnosis [ Time Frame: Day 0 ]

Central Contacts

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