Maternal Cardiovascular Adaption to Pregnancy in IVF Patients Following Frozen Embryo Transfer (FET)

Sponsor
Aalborg University Hospital
Study ID
NCT06471140
Status
Enrolling By Invitation

Conditions

  • Cardiovascular Adaption
  • Frozen Embryo Transfer (FET)
  • IVF
  • Magnetic Resonance Imaging (MRI)
  • Preeclampsia

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 40 Years
Healthy Volunteers
Accepted

Interventions

  • magnetic resonance imaging (MRI) — OTHER
    MRI performed three times during pregnancy and 6 months postpartum

Study Details

Aim of the study is to explore the effect of a lacking corpus luteum on maternal cardiovascular and metabolic adaption to pregnancy by the use of magnetic resonance imaging (MRI).

Key Dates

First listed
Jun 24, 2024
Start date
Mar 1, 2025
Status verified
May 2025
Primary completion
Aug 1, 2027
Completion
Aug 1, 2028

Study Design

Enrollment
75 participants (estimated)

Arms

  • Arm: IVF-pregnancy achieved following modified natural FET cycle, autologous embryo transfer
    One corpus luteum, control group, autologous embryo transfer
  • Arm: IVF-pregnancy achieved following programmed FET cycle, autologous embryo transfer
    No corpus luteum, study group, autologous embryo transfer
  • Arm: IVF-pregnancy achieved following egg donation in a FET cycle
    One corpus luteum or no corpus luteum, study group, donor egg recipient.

Primary Outcome Measure

Maternal cardiovascular adaption to pregnancy [ Time Frame: From early pregnancy to six months postpartum ]

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