DYNAMic Renal Assessment: NOvel Methods to Assess KIDNEY Functional Reserve

Sponsor
King's College Hospital NHS Trust
Study ID
NCT06572215
Status
Recruiting
Apply to this trial

Conditions

  • Chronic Kidney Diseases

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Dapagliflozin — DRUG
    On Day 3 to 16, participants will take 10mg dapaglifozin (SGLT-2 inhibitor) orally once daily.

Study Details

This is a feasibility study to assess new, more practical ways of measuring renal reserve.

Key Dates

Start date
Dec 14, 2023
Status verified
Mar 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
44 participants (estimated)

Arms

  • Arm: Healthy Participants
  • Arm: Patients with hyperfiltration

Primary Outcome Measure

Change in eGFR from baseline to 2hours after oral protein load [ Time Frame: 2 hours ]

Central Contacts

Related Studies