A Phase 1 Study of IM-1021 in Participants With Advanced Cancer

Part of paid clinical trials in Duarte, California.

Sponsor
Immunome, Inc.
Study ID
NCT06823167
Phase
PHASE1
Status
Recruiting
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Conditions

  • Hematologic Malignancies
  • Solid Malignancies

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • IM-1021 — BIOLOGICAL
    IM-1021 is an antibody-drug conjugate

Study Details

IM-1021-101 is a Phase 1 study to determine the safety and effectiveness of IM-1021 in treating participants with advanced cancer.

Key Dates

First listed
Feb 12, 2025
Start date
Feb 26, 2025
Status verified
Apr 2026
Primary completion
May 31, 2028
Completion
Feb 28, 2029

Study Design

Enrollment
117 participants (estimated)
Allocation
NA
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: Treatment Arm
    IM-1021 administered intravenously on a 21-day cycle, at a starting dose of 2 mg/kg.

Primary Outcome Measure

Safety and tolerability of IM-1021 in participants with advanced lymphomas and advanced solid tumors as measured by incidence of treatment emergent adverse events (TEAEs) [ Time Frame: From first dose to 37 days following last dose of study treatment ]

Central Contacts

Locations (17)

FacilityCityStateZIPSite coordinators
City Of HopeDuarteCalifornia91010-
University of CaliforniaLos AngelesCalifornia90095-
Colorado Blood Cancer InstituteDenverColorado80218-
Yale University Medical CenterNew HavenConnecticut06510-
Emory Winship Cancer InstituteAtlantaGeorgia30322-
University of IowaIowa CityIowa52242-
Norton Cancer InstituteLouisvilleKentucky40202-
University of MichiganAnn ArborMichigan48109-
START MidwestGrand RapidsMichigan49546-
University of Nebraska Medical CenterOmahaNebraska68105-
Levine Cancer InstituteCharlotteNorth Carolina28204-
Gabrail Cancer CenterCantonOhio44718-
Brown UniversityProvidenceRhode Island02903-
Sarah Cannon Research Institute - Oncology PartnersNashvilleTennessee37203-
MD Anderson Cancer CenterHoustonTexas77030-
NEXT OncologyIrvingTexas75039-
UT San Antonio Mays CancerSan AntonioTexas78229-

Find similar trials in Duarte, CA

By research site
City Of Hope· Duarte, CAUniversity of California· Los Angeles, CAColorado Blood Cancer Institute· Denver, COYale University Medical Center· New Haven, CTEmory Winship Cancer Institute· Atlanta, GAUniversity of Iowa· Iowa City, IA

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