Infectious Complications After Esophagectomy

Sponsor
Assistance Publique - Hôpitaux de Paris
Study ID
NCT06911658
Status
Recruiting
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Conditions

  • Esophagectomy
  • Infections
  • Pneumonia
  • Postoperative Complications

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Infectious complications represent the most common postoperative adverse events following esophagectomy for cancer, such as pneumonia (15% of cases). These complications increase immediate risks, lengthen hospital stays, and worsen patient quality of life. The population includes patients admitted to intensive care after esophagectomy for cancer between January 1, 2017, and December 31, 2024. The study focuses on this population due to the increasing incidence of esophageal cancer, the increased use of surgery for these indications, and the importance of postoperative infections in these complex procedures, despite their understudied nature in the current literature. Identifying modifiable risk factors could lead to corrective measures and thus improve the prognosis of postoperative patients. The research focuses primarily on the incidence, types, factors, and prognosis associated with the occurrence of infections after esophagectomy for cancer. It also includes an analysis of the pathogens involved, their resistance profiles, and the antibiotic therapies used in first-line probabilistic treatment.

Key Dates

First listed
Apr 4, 2025
Start date
Aug 27, 2025
Status verified
Dec 2025
Primary completion
Jul 28, 2026
Completion
Jul 28, 2026

Study Design

Enrollment
350 participants (estimated)

Primary Outcome Measure

Incidence of infections after esophagectomy for cancer [ Time Frame: until the day 28 ]

Central Contacts

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