Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients

Sponsor
University Hospital Ostrava
Study ID
NCT06921746
Status
Recruiting
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Conditions

  • Overactive Bladder

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Urine Microbiological and Metabolomic Analysis — DIAGNOSTIC_TEST
    Microbiological and metabolomic analysis of a urine sample will be performed in the study subjects, before and after the end of the treatment.

Study Details

This is a non-interventional study that will not pose any burden for the participants. The study subjects will be examined and treated in a standard manner according to current clinical recommendations for the treatment of overactive bladder (OAB). A portion of urine samples, which are routinely collected for biochemical and culture examinations as part of the diagnostic process, will be sent for examination of the characteristics of the urinary microbiome and metabolome (UMM) before and after treatment.

Key Dates

First listed
Apr 10, 2025
Start date
May 1, 2025
Status verified
May 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2027

Study Design

Enrollment
80 participants (estimated)

Arms

  • Arm: Overactive Bladder Patients
    Patients with the symptoms of overactive bladder will be enrolled in this study group

Primary Outcome Measure

Proportion of responders to the OAB treatment [ Time Frame: 6 weeks ]

Central Contacts

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