European Registry of Acutely Decompensated Pulmonary Arterial Hypertension

Sponsor
Assistance Publique - Hôpitaux de Paris
Study ID
NCT06923917
Status
Not Yet Recruiting

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Conditions

  • Pulmonary Hypertension

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Study Details

Acute decompensation of pulmonary hypertension (PH) is associated with a very unfavorable short-term prognosis. However, the development of circulatory support techniques and the possible use of emergency transplantation in recent years has significantly changed the management of patients with refractory right ventricular failure. Nonetheless, there are significant disparities in the management of these patients depending on the organization of the care pathway, the rules for graft allocation, and access to circulatory support across European countries. Moreover, the implementation of these new therapeutic strategies requires the identification of effective prognostic factors and the development of new monitoring techniques. The objective of this collaborative clinical research project is to study the prognostic implications of acute decompensated right heart failure associated with PAH based on a large-scale European multicenter approach using a prospective analysis of clinical, biological, and echocardiographic data.

Key Dates

First listed
Apr 11, 2025
Start date
Dec 1, 2025
Status verified
Nov 2025
Primary completion
Dec 1, 2028
Completion
Dec 1, 2029

Study Design

Enrollment
200 participants (estimated)

Arms

  • Arm: Patient with a confirmed diagnosis of pulmonary arterial hypertension managed for acute right hear

Primary Outcome Measure

3-months mortality/lung transplantation [ Time Frame: 3-months post inclusion ]

Central Contacts

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