Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis

Sponsor
Assistance Publique - Hôpitaux de Paris
Study ID
NCT07010250
Status
Not Yet Recruiting

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Conditions

  • ANCA Associated Vasculitis
  • Diabetic Nephropathies
  • Extramembranous Glomerulopathy
  • IgA Nephropathy
  • Interstitial Nephritis
  • Nephrotic Syndrome, Minimal Change
  • Segmental Hyalinosis

Eligibility Criteria

Sex
ALL
Age
18 Years - 90 Years
Healthy Volunteers
Not accepted

Study Details

The project is to explore in humans the hypothesis of the link between the alteration of tubulo-interstitial metabolism and the rate of deterioration of renal function by comparing various nephropathies.

Key Dates

Start date
Jun 2, 2025
Status verified
May 2025
Primary completion
Jun 2, 2029
Completion
Jun 2, 2029

Study Design

Enrollment
146 participants (estimated)

Arms

  • Arm: ANCA Associated Vasculitis
    Case
  • Arm: Extramembranous Glomerulopathy
    Control
  • Arm: Nephrotic Syndrome, Minimal Change
    Control
  • Arm: Interstitial Nephritis
    Control
  • Arm: IgA Nephropathy
    Control
  • Arm: Segmental Hyalinosis
    Control
  • Arm: Diabetic Nephropathy
    Control

Primary Outcome Measure

Spatial lipidomics for measuring tubular dysmetabolism [ Time Frame: Through study completion up to end of study, when the last patients completed 1 year follow-up. ]

Central Contacts

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