Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

Part of paid clinical trials in Anniston, Alabama.

Sponsor
Marea Therapeutics
Study ID
NCT07028749
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

  • Hypertriglyceridemia

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • MAR001 — DRUG
    Subcutaneous Injection
  • Placebo — DRUG
    Subcutaneous injection

Study Details

The primary objective of the study is to evaluate the effect of MAR001 compared to placebo on levels of TG in adults with elevated TG and RC.

Key Dates

First listed
Jun 19, 2025
Start date
Jun 30, 2025
Status verified
Aug 2026
Primary completion
Nov 30, 2027
Completion
Apr 30, 2028

Study Design

Enrollment
316 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: MAR001 Dose 1 (Part A)
    Subcutaneous injection
  • Experimental: MAR001 Dose 2 (Part A)
    Subcutaneous Injection
  • Experimental: MAR001 Dose 3 (Part A)
    Subcutaneous Injection
  • Experimental: MAR001 Dose 4 (Part B)
    Subcutaneous Injection

Primary Outcome Measure

Primary Endpoint [ Time Frame: 12 weeks ]

Central Contacts

Locations (26)

FacilityCityStateZIPSite coordinators
Marea Site 328AnnistonAlabama36207-
Marea Site 329MobileAlabama36608-
Marea Site 313Little RockArkansas72204-
Marea Site 306HamdenConnecticut06517-
Marea Site 302Boca RatonFlorida33434-
Marea Site 307Port Saint LucieFlorida34952-
Marea Site 310ColumbusGeorgia31904-
Marea Site 319Peachtree CornersGeorgia30092-
Marea Site 317Park RidgeIllinois60068-
Marea Site 325SpringfieldIllinois62702-
Marea Site 301LouisvilleKentucky40213-
Marea Site 316BaltimoreMaryland21229-
Marea Site 330Kansas CityMissouri64151-
Marea Site 305St LouisMissouri63110-
Marea Site 304Great NeckNew York11021-
Marea Site 318New WindsorNew York12553-
Marea Site 303GreensboroNorth Carolina27405-
Marea Site 315Winston-SalemNorth Carolina27104-
Marea Site 314GreenvilleSouth Carolina29607-
Marea Site 320Little RiverSouth Carolina29566-
Marea Site 326MemphisTennessee38119-
Marea Site 322AmarilloTexas79124-
Marea Site 308McKinneyTexas75071-
Marea Site 312San AntonioTexas78229-
Marea Site 321ManassasVirginia20109-
Marea Site 309TacomaWashington98405-

Find similar trials in Anniston, AL

By research site
Marea· Anniston, ALMarea· Mobile, ALMarea· Little Rock, ARMarea· Hamden, CTMarea· Boca Raton, FLMarea· Port Saint Lucie, FL

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