Observational Study on APL-like aCute Myeloid Leukemia: disTInct Phenotype and Early VAscular complicaTions

Sponsor
Gruppo Italiano Malattie EMatologiche dell'Adulto
Study ID
NCT07080970
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • observation of incidence of early vascular events — OTHER
    observation of difference incidence of early vascular events in the two cohorts

Study Details

This is a multicenter observational study with a retrospective and a prospective cohort investigating clinically and biologically the APL-like subset as a potential predictor of coagulopathy and susceptibility to early vascular events.

Key Dates

First listed
Jul 23, 2025
Start date
Jul 31, 2026
Status verified
Jun 2026
Primary completion
Dec 31, 2027
Completion
Nov 30, 2028

Study Design

Enrollment
220 participants (estimated)

Arms

  • Arm: APL-like
    NPM1 AML patients identified as APL-like cohort
  • Arm: Non APL-like
    NPM1 AML patients identified as no APL-like cohort

Primary Outcome Measure

Incidence of early vascular events [ Time Frame: 30 days from diagnosis ]

Central Contacts

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