Assessment of Composite Inflammatory Ratios in Juvenile Idiopathic Arthritis and Their Association With Disease Activity

Sponsor
Sohag University
Study ID
NCT07083466
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - 16 Years
Healthy Volunteers
Accepted

Interventions

  • complete blood count — DIAGNOSTIC_TEST
    blood test
  • serum albumin — DIAGNOSTIC_TEST
    blood test

Study Details

Juvenile Idiopathic Arthritis (JIA) is a prevalent pediatric rheumatic disorder characterized by persistent inflammation of one or more joints in children and adolescents. This chronic condition is a major contributor to both short- and long-term morbidity and functional disability We aim in this study to investigate the role of CAR, PLR, NLR ,systemic inflammatory index (SII ) and NAR ( SII and NAR have never been evaluated before in JIA patients ) as potential markers of disease activity in patients with non-systemic JIA (nsJIA) .

Key Dates

Start date
Jul 15, 2025
Status verified
Jun 2025
Primary completion
Apr 15, 2026
Completion
Apr 15, 2026

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: case
    cases under 16y established diagnosis juvenile idiopathic arthritis
  • Arm: control
    below age 16 y not diagnosed with any autoimmune or systemic disease

Primary Outcome Measure

possibility to use crp to albumin level as novel biomarker to predict disease activity in juvenile 0idiopathic arthritis [ Time Frame: 6 months ]

Central Contacts

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