A Study of LY3549492 in Healthy Weight Adult Participants

Part of paid clinical trials in Scottsdale, Arizona.

Sponsor
Eli Lilly and Company
Study ID
NCT07085468
Phase
PHASE2
Status
Terminated

Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
55 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • LY3549492 — DRUG
    Administered orally
  • Placebo — DRUG
    Administered orally

Study Details

The main purpose of this study is to evaluate the safety and tolerability of LY3549492 in adult participants with a healthy body max index (BMI) of 22 to 25 kilograms per square meter (kg/m2). Participation in the study will last about 13 months.

Key Dates

First listed
Jul 25, 2025
Start date
Jul 21, 2025
Status verified
Sep 2026
Primary completion
Aug 14, 2025
Completion
Aug 14, 2025

Study Design

Enrollment
1 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: 15 mg LY3549492
    Participants were planned to receive 15 milligrams (mg) LY3549492 orally once daily for 48 weeks.
  • Experimental: 60 mg LY3549492
    Participants were planned to receive 60 mg LY3549492 orally once daily for 48 weeks.
  • Placebo Comparator: Placebo
    Participants were planned to receive matching placebo orally once daily for 48 weeks.

Primary Outcome Measure

Number of Participants With One or More Serious Adverse Events (SAE) Considered by the Investigator to be Related to Study Drug Administration [ Time Frame: Baseline through Week 48 ]

Locations (11)

FacilityCityStateZIPSite coordinators
Headlands Research - ScottsdaleScottsdaleArizona85260-
Valley Clinical Trials, Inc.CovinaCalifornia91723-
Valley Clinical Trials, Inc.NorthridgeCalifornia91325-
Peninsula Research AssociatesRolling Hills EstatesCalifornia90274-
Artemis Institute for Clinical ResearchSan DiegoCalifornia92103-
JEM Research InstituteAtlantisFlorida33462-
Clinical Research AtlantaStockbridgeGeorgia30281-
Great Lakes Clinical Trials - AndersonvilleChicagoIllinois60640-
Alliance for Multispecialty Research, LLCLexingtonKentucky40509-
Alliance for Multispecialty Research, LLCNormanOklahoma73069-
Trial Management AssociatesMyrtle BeachSouth Carolina29572-

Find similar trials in Scottsdale, AZ

By research site
Headlands Research - Scottsdale· Scottsdale, AZValley Clinical Trials, Inc.· Covina, CAValley Clinical Trials, Inc.· Northridge, CAPeninsula Research Associates· Rolling Hills Estates, CAArtemis Institute for Clinical Research· San Diego, CAJEM Research Institute· Atlantis, FL

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