Delirium and Cognitive Impairment Development in Hospitalized Older Adults Under Isolation Conditions

Sponsor
Universitätsklinikum Hamburg-Eppendorf
Study ID
NCT07114458
Status
Recruiting
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Conditions

  • Cognitive Impairment
  • Delirium
  • Dementia

Eligibility Criteria

Sex
ALL
Age
70 Years - N/A
Healthy Volunteers
Not accepted

Study Details

The goal of this observational study is to examine if older patients who need to be under isolation precautions due to multidrug resistant bacteria or other reasons have an increased risk of suffering from delirium or cognitive decline compared to older patients without isolation precautions. To compare this, every person under isolation precautions is compared to other persons of the same age, gender, comorbidities, frailty status and hospital department. Delirium is assessed twice daily with a screening tool named 3D-CAM and cognitive performance is tested by the MOCA-Test six weeks after discharge from hospital and compared to baseline values which are assessed directly after study enrollment. The study duration for each patient participating is from the time of enrollment during hospitalization until 6 weeks after hospital discharge.

Key Dates

First listed
Aug 11, 2025
Start date
Aug 5, 2025
Status verified
Jul 2026
Primary completion
Apr 30, 2027
Completion
Nov 30, 2027

Study Design

Enrollment
404 participants (estimated)

Arms

  • Arm: Exposition
    Patients under isolation precautions in hospital
  • Arm: Control
    Matched control, no isolation precautions

Primary Outcome Measure

Delirium [ Time Frame: day 1-5 under isolation precautions ]

Central Contacts

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