Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore

Sponsor
National Cancer Centre, Singapore
Study ID
NCT07116161
Status
Recruiting
Apply to this trial

Conditions

  • Breast Cancer Female
  • Fatigue

Eligibility Criteria

Sex
FEMALE
Age
21 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Graded Exercise Therapy Arm (GET) — OTHER
    Consists of a self-supervised individualized exercise prescription by the rehabilitation professional consisting of aerobic (e.g. brisk walking / cycling) and resistance training exercises, customized by patient preference.
  • Experimental: Exercise Therapy (GET) plus Cognitive Behavioural Therapy (CBT) — OTHER
    Consists of four major components adapted from previous studies,13,15,16 and delivered by qualified and trained study psychologists. First, the ABCD model of cognitive behavioural therapy (A: activating events, B: beliefs, C: consequences, D: Dispute) will be taught and applied to identify negative, unhelpful beliefs and the emotional, behavioural and physical consequences of those beliefs. Second, patients were taught behavioural strategies to manage fatigue (e.g. sleep hygiene, activity scheduling). Lastly, participants will be guided to reformulate dysfunctional cognitions regarding fatigue, improve coping strategies in relation to significant others (e.g. family, friends) and set goals.

Study Details

The purpose of this research study is to investigate the acceptability, feasibility, and effectiveness of exercise therapy and cognitive behavioral therapy (CBT) in improving fatigue levels and breast cancer treatment adherence in breast cancer patients.

Key Dates

First listed
Aug 11, 2025
Start date
Jul 14, 2025
Status verified
May 2026
Primary completion
Apr 30, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH

Arms

  • Experimental: Graded Exercise Therapy Arm (GET)
  • Experimental: Exercise Therapy (GET) plus Cognitive Behavioural Therapy (CBT)

Primary Outcome Measure

Client Satisfaction with Exercise Therapy and Cognitive Behavioural Therapy (CBT) [ Time Frame: Up to 12 months post-enrolment. ]

Central Contacts

Related Studies