Accelerated Rotational Field Deep TMS for Treating OCD

Sponsor
Ben-Gurion University of the Negev
Study ID
NCT07116785
Status
Recruiting
Apply to this trial

Conditions

  • Obsessive-Compulsive Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • BrainsWay Deep TMS HAC/H7-Coil — DEVICE
    Rotational field TMS (rfTMS) is a novel technology where two orthogonal coils are operated with a 90 phase shift between them. The combined electric field vector of rfTMS from both coils rotates up to a complete cycle during the TMS pulse. This method overcomes the inherent limitation of conventional unidirectional TMS by influencing neurons in various orientations (Roth et al., 2020b). This unique advance bears enormous potential for therapeutic applications in various neuropsychiatric disorders. The coil Array includes the H7 coil as the lower coil, and an upper coil perpendicular to it. Hence, the HAC/H7 coil Array induces similar electric field distribution and affects the same brain structures as the H7 coil, but stimulates neurons in various orientations within these regions.
  • BrainsWay Deep TMS Sham Coil — DEVICE
    Participants assigned to this intervention will receive sham stimulation using a BrainsWay Deep TMS sham coil that mimics the sensation and acoustic properties of active stimulation but does not deliver effective magnetic pulses to the brain. This condition is used as a placebo control to blind participants and investigators.

Study Details

A Prospective Double Blind Randomized Controlled Trial to Evaluate the Efficacy and Durability of the BrainsWay Rotational Field Deep Transcranial Magnetic Stimulation (Deep TMS) in Obsessive-Compulsive Subjects

Key Dates

First listed
Aug 12, 2025
Start date
Sep 19, 2023
Status verified
Aug 2025
Primary completion
Jun 14, 2027
Completion
Dec 14, 2028

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Active TMS
  • Sham Comparator: Sham TMS

Primary Outcome Measure

Yale Brown Obsessive Compulsive Scale (YBOCS) [ Time Frame: 6 weeks ]

Central Contacts

Related Studies