Regional Anesthesia in TKA: Impact on Postoperative Joint Motion and Patient Satisfaction

Sponsor
Konya City Hospital
Study ID
NCT07124494
Status
Recruiting
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Conditions

  • Knee Range of Motion
  • Patient Satisfaction
  • Postoperative Pain
  • Regional Anesthesia
  • Total Knee Arthroplasty

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Regional anethesia — PROCEDURE
    This single-center, prospective, randomized controlled trial aims to compare the effects of three different postoperative analgesia techniques following spinal anesthesia in patients undergoing total knee arthroplasty (TKA). The study will assess the impact of combined spinal-epidural anesthesia, adductor canal block, and multimodal intravenous analgesia on postoperative knee range of motion (ROM). Secondary outcomes include patient satisfaction, opioid consumption, Oxford Knee Score (OKS), activity levels, and visual analog scale (VAS) pain scores.

Study Details

This is a single-center, prospective, randomized controlled trial aiming to evaluate the effects of different regional anesthesia/analgesia techniques on postoperative knee range of motion (ROM) and patient satisfaction following total knee arthroplasty (TKA). Ninety patients undergoing elective TKA under spinal anesthesia will be randomly assigned to one of three groups: 1) spinal anesthesia with epidural catheter, 2) spinal anesthesia followed by adductor canal catheterization, and 3) spinal anesthesia with multimodal intravenous analgesia. The primary outcome is postoperative knee joint ROM measured on postoperative days 1, 2, and 3. Secondary outcomes include patient satisfaction, Oxford Knee Score, postoperative opioid consumption, and VAS scores. The study is conducted at Konya City Hospital and will be completed over a 6-month period.

Key Dates

First listed
Aug 15, 2025
Start date
Aug 5, 2025
Status verified
Jul 2026
Primary completion
Dec 12, 2026
Completion
Dec 19, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Combined Spinal-Epidural Anesthesia
    Postoperative analgesia will be provided via epidural catheter with programmed infusion of bupivacaine .
  • Active Comparator: Adductor Canal Block
    Ultrasound-guided adductor canal catheter placement and continuous infusion of bupivacaine .
  • Sham Comparator: Multimodal Intravenous Analgesia
    Continuous intravenous tramadol infusion with rescue analgesia as required.

Primary Outcome Measure

Postoperative Knee Range of Motion (ROM) [ Time Frame: Postoperative day 1, day 3, day 7, and day 90 after surgery. ]

Central Contacts

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