Mediterranean Diet in Familial Mediterranean Fever: Is Fatty Liver Affected by Addition of Aerobic Exercise

Sponsor
Cairo University
Study ID
NCT07130318
Status
Recruiting
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Conditions

  • Familial Mediterranean Fever
  • Non-Alcoholic Fatty Liver Disease

Eligibility Criteria

Sex
FEMALE
Age
30 Years - 55 Years
Healthy Volunteers
Not accepted

Interventions

  • exercise plus diet restriction — BEHAVIORAL
    Familial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months. also, this group, Group I, will also perform elliptical aerobic exercise (this exercise will be applied for 40 minutes three times weekly and this exercise will be maintained for 6 months)
  • diet restriction — BEHAVIORAL
    Familial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months.

Study Details

Familial Mediterranean fever (FMF) affect liver and causes some dysfunctions including non-alcoholic fatty liver.. still exercise and diet limitation is the treatment for this case

Key Dates

First listed
Aug 19, 2025
Start date
May 8, 2025
Status verified
Aug 2025
Primary completion
Jan 8, 2026
Completion
Jan 8, 2026

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: group number 1
    Familial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months. also, this group, Group I, will also perform elliptical aerobic exercise (this exercise will be applied for 40 minutes three times weekly and this exercise will be maintained for 6 months)
  • Active Comparator: group number 2
    Familial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months.

Primary Outcome Measure

aspartate transaminase [ Time Frame: it will be measured after 6 months ]

Central Contacts

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