Intraocular Lens Calculation Using Artificial Intelligence

Sponsor
Johannes Kepler University of Linz
Study ID
NCT07202767
Status
Not Yet Recruiting

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Conditions

  • Cataract

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Swept-Source Anterior Segment OCT — DEVICE
    Device: Swept-Source Anterior Segment OCT The CASIA-2 (Tomey, Japan) is a high-resolution swept-source anterior segment OCT with CE certification. The device allows for incomplete visualization of the lens, including the anterior and posterior lens curvature. Device: AS-OCT + Placido disc corneal topography The MS-39 (CSO, Italy) is a non-invasive device that combines Placido topography with OCT-based anterior segment tomography. Device: Wave-front abberomtery The OSIRIS aberrometer is a standard tool for examining corneal aberration and measuring the ocular wavefront. Device: Swept-Source OCT The IOLMaster 700 (Carl Zeiss Meditec, Germany) is a standard swept-source OCT used for eye examinations. Device: AS-OCT The ANTERION (Heidelberg Engineering, Germany) is an anterior segment swept-source OCT. Diagnostic Test: Refraction Subjective Refraction evaluation using the cross-cylinder method

Study Details

The aim of this study is to investigate the lens diameter (LD) as a useful parameter in intraocular lens (IOL) power calculation by using several different non-invasive imaging techniques. The aim is to establish an accurate model for lens diameter estimation and subsequently evaluate the influence of the LD on the effective postoperative lens position. The comparability of the different devices in terms of variability between the biometric measurements will also be assessed. By then combining these two approaches with artificial intelligence, the aim is to develop a new approach to effectively incorporate the LD in IOL power calculation and improve patient's outcome in the long run.

Key Dates

First listed
Oct 2, 2025
Start date
Nov 1, 2025
Status verified
Oct 2025
Primary completion
Jul 30, 2027
Completion
Oct 30, 2028

Study Design

Enrollment
170 participants (estimated)

Arms

  • Arm: Study Cohort with MRI
    Patients who are included in this study who additionally receive a cerebral MRI
  • Arm: Study cohort without MRI
    Study cohort who doesn't receive an MRI

Primary Outcome Measure

Prediction model to estimate lens diameter with different measurement tools (swept-AS segment OCT; anterior segment-OCT and Placido topography with OCT-based anterior segment tomography; wave-front abberometry; swept-source OCT and optical biometer) [ Time Frame: preoperatively, 4 and 12 weeks post cataract surgery ]

Central Contacts

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