Effects of Various Cannabis Strains on Perceptual, Subjective and Objective Use Outcomes

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT07214155
Phase
PHASE1
Status
Recruiting
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Conditions

  • Cannabis Intoxication

Eligibility Criteria

Sex
ALL
Age
21 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • Cannabis — DRUG
    Cannabis will be administered via smoked inhalation.
  • 0 mg THC (placebo) — OTHER
    0 mg THC (placebo)

Study Details

This study will evaluate the subjective and behavioral effects of cannabis products labeled as indica, sativa, or generic.

Key Dates

First listed
Oct 9, 2025
Start date
Sep 15, 2026
Status verified
Sep 2026
Primary completion
Jun 30, 2029
Completion
Sep 30, 2029

Study Design

Enrollment
70 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Placebo Comparator: Indica-Labeled Cannabis - Placebo
    Participants administer smoked cannabis labeled as indica containing 0mg THC.
  • Placebo Comparator: Sativa-Labeled Cannabis - Placebo
    Participants administer smoked cannabis labeled as Sativa containing 0mg THC.
  • Placebo Comparator: Generically-Labeled Cannabis - Placebo
    Participants administer smoked cannabis labeled generically containing 0mg THC.
  • Experimental: Indica-Labeled Cannabis - Active
    Participants administer smoked cannabis labeled as indica containing 25mg THC.
  • Experimental: Sativa-Labeled Cannabis - Active
    Participants administer smoked cannabis labeled as sativa containing 25mg THC.
  • Experimental: Generically-Labeled Cannabis - Active
    Participants administer smoked cannabis labeled generically containing 25mg THC.

Primary Outcome Measure

Number of Correct Trials on Paced Auditory Serial Addition Task (PASAT) [ Time Frame: Baseline, 0-, 1-, 1.5-, 2-, 3-, 4-, 5-, and 6-hours post-dosing ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Johns Hopkins UniversityBaltimoreMaryland21224
Carlos A Zamarripa, PhD
[email protected]
410-550-6969

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By research site
Johns Hopkins University· Baltimore, MD

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