Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation

Part of paid clinical trials in Duarte, California.

Sponsor
City of Hope Medical Center
Study ID
NCT07235501
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
7 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Non-Interventional Study — OTHER
    Non-interventional study

Study Details

This study evaluates the factors that contribute to chronic graft-versus-host disease, which is a complication that can occur after allogeneic hematopoietic cell transplantation.

Key Dates

First listed
Nov 19, 2025
Start date
Oct 1, 2026
Status verified
Jul 2026
Primary completion
Jan 17, 2030
Completion
Jan 17, 2030

Study Design

Enrollment
75 participants (estimated)

Arms

  • Arm: Observational Cohort 1
    Patients undergo blood, saliva/buccal, and stool sample collection for up to 2 years on study. Patients also have their medical records reviewed on study.
  • Arm: Observational Cohort 2
    Patients undergo a one-time blood, saliva/buccal, and stool sample collection and have their medical records reviewed on study.

Primary Outcome Measure

T cell measurements [ Time Frame: Up to 2 years - study completion ]

Locations (1)

FacilityCityStateZIPSite coordinators
City of Hope Medical CenterDuarteCalifornia91010
Ryotaro Nakamura
[email protected]
626-218-2405
Ryotaro Nakamura (PRINCIPAL_INVESTIGATOR)

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By research site
City of Hope Medical Center· Duarte, CA

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