Role of Alprazolam in Management of Post Endodontic Pain After Single Visit Root Canal Treatment. To Compare Mean Pain Score Between Two Group of Participants Undergoing Post Operative Pain Management After Single Visit Root Canal Treatment: NSAIDs Alone and a Combination of NSAIDs and Alprazolam.

Sponsor
Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi
Study ID
NCT07275710
Status
Recruiting
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Conditions

  • Pain

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • Brufen and alprazolam — COMBINATION_PRODUCT
    second group in the study will be prescribed 400mg ibuprofen and 0.5mg alp tablet for management of post endodontic pain after root canal treatment
  • Brufen — DRUG
    one group in the study will be prescribed 400mg ibuprofen for management of post endodontic pain after root canal treatment

Study Details

To compare mean pain score between two group of participants undergoing post operative pain management after single visit root canal treatment: one group receiving NSAIDs alone and the other receiving a combination of NSAIDs and an anxiolytic medication i.e alprazolam.

Key Dates

First listed
Dec 10, 2025
Start date
Jul 30, 2026
Status verified
Jul 2026
Primary completion
Jan 1, 2027
Completion
Feb 1, 2027

Study Design

Enrollment
110 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Active Comparator: brufen
    one group in the study will be prescribed 400mg ibuprofen tablet for management of post endodontic pain after root canal treatment and patient will be asked to score their pain level at 6, 12 and 24 hours on visual analogue scale.
  • Active Comparator: alprazolam
    second group in the study will be prescribed 0.5mg alp tablet for management of post endodontic pain after root canal treatment and patient will be asked to score their pain level at 6, 12 and 24 hours on visual analogue scale.

Primary Outcome Measure

pain levels [ Time Frame: 6 hours 12 hours 24 hours ]

Central Contacts

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