PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

Conditions

• Distal Esophageal Spasm
• EGJ Outflow Obstruction With Spastic/Hypercontractile Features
• Jackhammer Esophagus
• Type III Achalasia

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Study Details

The goal of this observational study is to learn about how the doctor decides how long to cut t the esophageal muscle during Per-Oral Endoscopic Myotomy (POEM) in patients with difficulty swallowing due to certain conditions. The main question it aims to answer is: does pre-POEM testing help the physician choose how long to cut the muscle. Participants will allow researchers to access their standard of care information in their medical record, complete questionnaires at up to 6 times over a 2-year period.

Key Dates

First listed

Dec 19, 2025

Start date

Dec 1, 2026

Status verified

Aug 2026

Primary completion

Aug 31, 2031

Completion

Aug 31, 2032

Study Design

Enrollment

200 participants (estimated)

Primary Outcome Measure

Clinical Response-Overall [ Time Frame: From enrollment to Year 2 ]

Central Contacts

• Elizabeth Yan, BS
  312-908-1723
  [email protected]
• Yasmin Pina, BS
  312-503-6459
  [email protected]

Locations (15)

Find similar trials in Scottsdale, AZ