Effect of TMS on Neuropathic Pain for Patients With Sci

Sponsor
Ankara Etlik City Hospital
Study ID
NCT07293780
Status
Recruiting
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Conditions

  • Neuropathic Pain
  • Spinal Cord Injury

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • active TMS — DEVICE
    Patients in the active or sham primary motor cortex rTMS group will receive active or sham rTMS at 5 Hz targeting the M1 area of the lower extremity motor area under medical supervision for a total of 10 sessions over 2 weeks. Patients in the active anterior cingulate cortex rTMS group will also receive active 5 Hz rTMS targeting the anterior cingulate cortex for a total of 10 sessions over 2 weeks under medical supervision.
  • sham TMS — DEVICE
    Patients in the active or sham primary motor cortex rTMS group will receive active or sham rTMS at 5 Hz targeting the M1 area of the lower extremity motor area under medical supervision for a total of 10 sessions over 2 weeks. Patients in the active anterior cingulate cortex rTMS group will also receive active 5 Hz rTMS targeting the anterior cingulate cortex for a total of 10 sessions over 2 weeks under medical supervision.

Study Details

The aim of this study is to evaluate the efficacy of rTMS targeting the anterior cingulate cortex, another stimulation site that may be effective in the treatment of neuropathic pain, and to compare it with motor cortex stimulation.

Key Dates

First listed
Dec 19, 2025
Start date
Dec 15, 2025
Status verified
Feb 2026
Primary completion
Aug 1, 2026
Completion
Nov 1, 2026

Study Design

Enrollment
39 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: active rTMS primer motor cortex
  • Experimental: rTMS anterior cingulate gyrus
  • Sham Comparator: sham rTMS primer motor cortex

Primary Outcome Measure

visual analog scale [ Time Frame: first day of treatment, at the end of treatment (at 2nd week), 4 week after end of treatment, 12 week after end of treatment ]

Central Contacts

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