Evaluation of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy for Treatment of Chemotherapy Induced Peripheral Neuropathy

Sponsor
Rijnstate Hospital
Study ID
NCT07304401
Status
Recruiting
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Conditions

  • Chemotherapy Induced Peripheral Neuropathy (CIPN)
  • Neuropathic Pain

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

The goal of this observational study is to learn about the effectiveness of closed-loop spinal cord stimulation (CL-SCS) therapy for treatment of painful chemotherapy induced peripheral neuropathy. The closed-loop SCS (CL-SCS) system stimulates the nerves in the spinal cord, measures their responses and automatically adjust the stimulation level accordingly in real time for each delivered pulse.

Key Dates

First listed
Dec 26, 2025
Start date
Dec 1, 2025
Status verified
Dec 2025
Primary completion
Dec 1, 2028
Completion
Dec 1, 2028

Study Design

Enrollment
20 participants (estimated)

Arms

  • Arm: Patients with painful chemotherapy induced peripheral neuropathy (CIPN)
    Subjects diagnosed with painful CIPN and eligible for SCS implantation

Primary Outcome Measure

Overall pain intensity [ Time Frame: The difference between baseline and the evaluation at 1, 3, 6 and 12 months after SCS implantation. ]

Central Contacts

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