A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS)

Sponsor
Charlotte Vogt
Study ID
NCT07341984
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • Individualized Physiotherapy — OTHER
    see above

Study Details

This study investigates whether an individualized physiotherapy program, tailored to each patient's specific motor deficits, can better support physical function compared with usual care physiotherapy in people with ALS. The individualized program is guided by diagnostic assessments using a robotic leg press system, which helps identify strengths and weaknesses in muscle function and movement control. Participants will receive either individualized physiotherapy or standard physiotherapy and will be followed for 12 months. The aim of the study is to improve physiotherapy strategies for people with ALS in a safe and patient-centered manner.

Key Dates

First listed
Jan 15, 2026
Start date
Dec 16, 2025
Status verified
Jan 2026
Primary completion
Dec 15, 2027
Completion
Dec 15, 2028

Study Design

Enrollment
38 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Individualized Physiotherapy Group
    This group receives an individualized physiotherapy program tailored to patient-specific functional deficits. Two thrids of participants are allocated to the intervention group.
  • Active Comparator: Usual Care Physiotherapy Group
    This group continues to receive usual care physiotherapy in accordance with standard clinical practice. One third of participants are allocated to the control group.

Primary Outcome Measure

Climbing stairs (ALSFRS-R [amyotrophic lateral sclerosis functional rating scale - revised] - item 9: score range 0 to 4 with 4 indicating normal function) [ Time Frame: 6 months ]

Central Contacts

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