The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia

Sponsor
University of British Columbia
Study ID
NCT07364019
Status
Recruiting
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Conditions

  • Cognitive Change
  • Dementia Education
  • Dementia Prevention
  • Lifestyle Intervention
  • Mild Cognitive Impairment
  • Subjective Cognitive Impairment

Eligibility Criteria

Sex
ALL
Age
50 Years - 80 Years
Healthy Volunteers
Accepted

Interventions

  • Brain Health PRO — OTHER
    Immediate start of 6-month Brain Health PRO Intervention
  • Brain Health PRO — OTHER
    Delayed start of 6-month Brain Health PRO

Study Details

This study will recruit participants at risk for dementia to participate in an online educational program called Brain Health PRO (BHPro). The BHPro intervention is designed to address modifiable risk factors for dementia through a 6-month, fully online, educational program conveying the best available evidence for lifestyle changes that can mitigate dementia risk, and foster engagement toward one's own brain health. Achieving lifestyle changes in a diverse Canadian population through online education would be a major achievement in dementia prevention in Canada, with widespread personal and socioeconomic benefits. Eligible participants will be randomly assigned to either start Brain Health PRO immediately or in 6 months (delayed-start control group). All participants will have the opportunity to have access to BHPro for 6 months during the course of the study and will have open access to all content for 12 months following the initial 6-month intervention. Participation will last from 18-24 months depending on group assignment.

Key Dates

First listed
Jan 23, 2026
Start date
May 7, 2026
Status verified
May 2026
Primary completion
Dec 31, 2028
Completion
Dec 31, 2028

Study Design

Enrollment
700 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION

Arms

  • Experimental: Immediate BHPro Intervention Group
    Participants in this group will start Brain Health PRO immediately at baseline
  • Other: Delayed Start BHPro
    Participants in this group will start Brain Health PRO in 6 months (delayed)

Primary Outcome Measure

Change in modifiable risk factors as measured by a 7-item composite dementia risk factor score after 6 months. [ Time Frame: Change from baseline to month 6 ]

Central Contacts

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